sissycjb 发表于 2012-7-27 10:29 static/image/common/back.gif
bluest,您好，昨天跟医生讨论了一下，因为我妈妈是肝脏多发，他不建议用放疗，基于我妈妈现在身体还可以承 ...
听医生的吧
bluest 发表于 2012-7-27 11:20 static/image/common/back.gif
听医生的吧
bluest,你好,我妈妈换紫杉醇做了第4个化疗,紫杉醇用量210mg,然后口服替吉奥9天,因为血色素降至6g,所以停止了替吉奥的口服,因为胆系感染,高烧和肩膀疼现在在医院进行消炎治疗,另外因为血色素下降到了5g,现在输了800cc血,CA199从化疗前5830降至1470,但是因为反应太大,医生不建议再进行化疗了,想问问您,如果我现在可以使用靶向药?能给我一些下步的治疗建议吗?看到情况好转,我不想放弃治疗,我想用一些其他的方法......
sissycjb 发表于 2012-8-16 15:08 static/image/common/back.gif
bluest,你好,我妈妈换紫杉醇做了第4个化疗,紫杉醇用量210mg,然后口服替吉奥9天,因为血色素降至6g,所以停止 ...
紫杉醇是副作用很大的一个药，以后再用可以尝试小剂量。先吃特罗凯吧，特不影响血象，利用这期间把血象养好。
bluest 发表于 2012-8-16 15:14 static/image/common/back.gif
紫杉醇是副作用很大的一个药，以后再用可以尝试小剂量。先吃特罗凯吧，特不影响血象，利用这期间把血象养 ...
bluest,你好,如果以后再用紫杉醇,剂量可以用多大啊?另外,我想问一下特罗凯从哪里能买到阿,我们这边的医院没有啊
本帖最后由 bluest 于 2012-8-16 17:20 编辑
sissycjb 发表于 2012-8-16 15:20 static/image/common/back.gif
bluest,你好,如果以后再用紫杉醇,剂量可以用多大啊?另外,我想问一下特罗凯从哪里能买到阿,我们这边的医院 ...
Abstract
The authors evaluated the activity and toxicity of docetaxel given as a 1-hour infusion every 21 days in patients with unresectable cholangiocarcinoma. Seventeen patients with cytologically or histologically confirmed cholangiocarcinoma received intravenous docetaxel over 1 hour, repeated every 21 days. The initial dose of docetaxel was 100 mg/m2, with a subsequent 25% dose reduction for patients experiencing grade 3 or 4 toxicities. Treatment was continued until disease progression or occurrence of intolerable side effects. All patients received premedication with dexamethasone 8 mg by mouth twice daily for 5 days, starting 1 day before docetaxel infusion. Sixteen of the 17 patients were assessable for response and toxicity; one patient was removed from the trial for intercurrent illness. Thirty-eight cycles of docetaxel were delivered (median, two cycles). No complete or partial responses were noted. Fourteen patients had progressive disease, one patient had stable disease, and one patient died of septic shock shortly after starting treatment. Granulocytopenia was the dose-limiting toxicity. Thirteen patients had grade 4 granulocytopenia, 11 of whom required antibiotics for neutropenic fever. Granulocytopenia was the only grade 4 toxicity observed. Grade 3 toxicities included stomatitis, anemia, fatigue, vomiting, and hypotension. Grade 1 or 2 toxicities included alopecia, diarrhea, peripheral edema, myalgias, and anorexia. Administered on this dose and schedule, docetaxel lacked activity in patients with cholangiocarcinoma. The toxicity profile, including dose-limiting granulocytopenia, has been previously described in patients receiving docetaxel.
这里有一个单药多西他赛治疗胆管癌的二期临床实验报告，多西的用量为100mg/平米（21天一次），如果不耐受剂量减少25%。
sissycjb 发表于 2012-8-16 15:20 static/image/common/back.gif
bluest,你好,如果以后再用紫杉醇,剂量可以用多大啊?另外,我想问一下特罗凯从哪里能买到阿,我们这边的医院 ...
请问你们的腹水是如何控制的？
jiaming77 发表于 2012-8-17 23:52 static/image/common/back.gif
请问你们的腹水是如何控制的？
我们就是打人血白蛋白，多吃一些利尿的食物
bluest 发表于 2012-8-16 16:57 static/image/common/back.gif
Abstract
The authors evaluated the activity and toxicity of docetaxel given as a 1-hour infusio ...
bluest,您好，我妈妈自从做完第四次化疗后，情况一直不稳定，持续高烧，最高温度达到42度，现在打了14天抗生素，控制住了，但是体温还是在37度多，肩膀疼，胃不太舒服，做了 血检，血色素由10g又降至8.5g，胆红素30多，直接胆红素和间接胆红素都高于正常范围，肌酐30多，低于正常值，谷草68高于正常值，现在口服优思佛和中药以及多糖类保健品，现在腿脚有点肿，CT显示：胸膜增厚，胸腔有少量积液；脾大，达到8个肋单位；肝脏多发，胆管轻度扩张，内见条状气体流；盆腔积液。CA199由4期化疗1470一个月内升置4541，一个月内没有做任何控制肿瘤治疗，就我妈妈现在的情况，您能给我一些建议吗？
本帖最后由 bluest 于 2012-9-13 10:53 编辑
sissycjb 发表于 2012-9-13 09:18 static/image/common/back.gif
bluest,您好，我妈妈自从做完第四次化疗后，情况一直不稳定，持续高烧，最高温度达到42度，现在打了14天抗 ...
这些反应就是化疗引起，长期连续化疗就会出现这些问题，只有停化疗慢慢恢复。我的建议和以前一样，化疗有效，别用到头，对长期治疗，对保护身体都有好处。医院的常规化疗方法是一直化疗到不耐受或肿瘤进展为止，到那时身体毁了，化疗也用尽了。化疗在初期的时候不会有大问题，一般人的身体都可以随，但如果不适度停止，长期连续化就会出问题。
现在胆管有扩张，黄疸已经来了，肯定是进展。我的建议是停化疗，直接上2992，越快越好。
bluest 发表于 2012-9-13 10:50 static/image/common/back.gif
这些反应就是化疗引起，长期连续化疗就会出现这些问题，只有停化疗慢慢恢复。我的建议和以前一样，化疗 ...
bluest,2992从哪里能买到阿?我们这里是小城市,医院里没有