平安！ 发表于 2011-11-9 19:57
) J- \) X3 u( Q: A$ r+ T0 p9 z1 mPazopanib (100 mg/kg/day free base equivalent)
这是个已经在美国上市的老药了，能下载到正式药物使用说明书英文版。) e- Q0 d& j) f$ Y
搜索了一下，原料一大堆。
7 W5 D8 P$ M; i1 Y1 n
1 ?" r. R! g7 Z& ^- I7 ~对不起！100mg/kg是用于移植瘤的，我弄错了。( D, A4 v: H7 C
8 H! p% D6 c3 A
以下是正版说明书的推荐用量。% n& _0 ^+ ~8 |/ ~) I& O
1 c5 {" p3 m5 x L8 G# S4 C# f2 b
--------------------- DOSAGE AND ADMINISTRATION ----------------
7 a V# Z. O# ~* f% Y7 Y4 }7 E8 L, B* 800 mg orally once daily without food (at least 1 hour before or 2 hours after a meal). (2.1) 4 y1 w1 Q+ D/ K, v- l' r. O
* Baseline moderate hepatic impairment – 200 mg orally once daily. Not recommended in patients with severe hepatic impairment. (2.2) 5 D" e- B. [& K
---------------------DOSAGE FORMS AND STRENGTHS --------------
) m' D# V" f5 K% u200 mg tablets. (3) ) o& I; t# Y9 y- n( d+ t! O
-------------------------------CONTRAINDICATIONS------------------------ |
11011102001537 )
显身卡
( O7 T# n6 c9 s$ o) r
