刚下了avastin官网的用药指南:' Z0 c* u2 }5 C/ j0 Z; k
: P) | k2 b' U/ S' l2 u7 h Patients should continue treatment until disease progression or unacceptable toxicity.
) r) M/ N! h" D0 _1 Metastatic Colorectal Cancer (mCRC) ! }7 I) S/ v3 Z% j- E/ s0 g. G. k
The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with
' v [, }8 V( Kintravenous 5-FU-based chemotherapy. 2 C/ ?; J$ U, M2 W/ d3 E7 [, V
• Administer 5 mg/kg when used in combination with bolus-IFL.
. ]1 F9 ~3 ^* I0 o• Administer 10 mg/kg when used in combination with FOLFOX4. 5 X- Z% |+ b' }
2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
3 g! [& o6 U7 \3 C" d* N+ i$ K6 e The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and
5 g. H2 A8 m3 j: H- ]# f+ Kpaclitaxel.
6 Y5 y- S. H, T. L$ [9 A3 Metastatic Breast Cancer (MBC) % x6 B- a4 u2 f
The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel. * {3 p/ k. \$ M; \ a9 J
4 Glioblastoma
; G+ y- D. [% v/ w& z$ v The recommended dose is 10 mg/kg every 2 weeks.
+ I5 w0 J% e, J3 ]: b/ ^2 ]5 Metastatic Renal Cell Carcinoma (mRCC)
: B/ ^ z* l0 B" f; }# m The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa. 3 F% ]0 ^3 z+ ]6 S4 Q. g9 W5 B; u
P7 u0 T0 K5 X0 [ [ K' A! y; A按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。- ^, D# n" ~: s4 T1 v" x
我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |